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▣▣▣ Welcome To Cell and Gene Therapy Lab. 전남대학교병원 세포치료연구실 ▣▣▣

 

 

Title:

Assistant Professor, Dept. of Biomedical Science, Chonnam National University Medical School

Business Address:

Dept. of Biomedical Sciences and Medical Research Center for Gene Regulation
Chonnam National Univ. Medical School
5, Hak-1-dong, Kwanju 501-746
Rep. of Korea  Tel: +82-62-220-4225  FAX: +82-62-228-4227
E-mail: pik96d@gmail.com / pik96@chonnam.ac.kr

Education:

Seoul National University B.S.  1996  Natural Fiber Science
Seoul National University M.S.  1998 Natural Fiber Science
Seoul National University Ph.D. 2002 School of Biological Resources and Engineering

Professional Experience:

2000.  9 ~ 2001. 2      Visiting Scientist, Tokyo Institute of Technology
2003. 10 ~ 2004. 3      Research Associate, Department of Biomolecular Engineering, Tokyo Institute of                                Technology.
2002.  4 ~ 2004. 8      Visiting Researcher, Research Institute for Agriculture and Life Sciences, Seoul National                                University
2004.  9 ~ 2005. 4      Senior Scientist, Research Institute for Agriculture and Life Sciences, Seoul National                               University
2005.  5 ~ 2007. 6      Senior Fellow, Dept. of Bioengineering, University of Washington.
2007.  6 ~ Present     Assistant Professor, Dept. of Biomedical Sciences, Chonnam National
                               University Medical School.

Main Thrust Areas

Tissue-targeted gene therapy (Heart, cancer, liver, neuron, etc.)
Design and characterization of tissue-specific molecular imaging contrast agents (MRI, Optical Imaging)
Development of Gene-activated matrix for enhanced tissue regeneration
Delivery systems of bioactive molecules (Vaccine, proteins)

 

Publication Lists

International Papers

1. In-Kyu Park, Y.H. Park, B.A. Shin, E.S. Choi, Y.R. Kim, T. Akaike, C.S. Cho, Galactosylated chitosan-graft-dextran as hepatocyte-targeting DNA carrier, J. Control. Release, 69 (2000) 97-108

2. In-Kyu Park, Y.H. Park, Preparation and structural characterization of water-soluble O-hydroxypropyl chitin derivatives, J. Appl. Polym. Sci., 80 (2001), 2624-2632

7. In-Kyu Park, T.H. Kim, H.Y. Kweon, Y.H. Park, W.J. Kim, T. Akaike, and C.S. Cho, Visualization of transfection of galactosylated chitosan-graft-poly(ethylene glycol) /DNA complexes into hepatocytes by confocal Laser Scanning Microscopy, Int. J. Pharm., 257 (2003) 103-110.

9. In-Kyu Park, J. Yang, H.J. Jeong, H.S. Bom, I. Harada. T. Akaike, S.I. Kim, C.S. Cho, Galactosylated chitosan as a synthetic extracellular matrix for hepatocytes attachment, Biomaterials, 24 (2003) 2331-2337.

10. In-Kyu Park, T.H. Kim, S.I. Kim, T. Akaike and C.S. Cho, Chemical modification of chitosan for the gene delivery, J. Dispersion Sci. Technol., 24 (2003) 489-498.

15. S.J. Seo, In-Kyu Park, M.K. Yoo, M.i Shirakawa, T. Akaike, C.S. Cho, Xyloglucan as a synthetic extracellular matrix for hepatocytes attachment, Journal of Biomaterials Science Polymer Ed., 15(11) (2004) 1375-1384.

17. H.L. Jiang, In-Kyu Park, N.R. Shin, H.S. Yoo, T. Akaike, C.S. Cho, Controlled Release of Vaccine from Bordetella Bronchiseptica Dermonecrotoxin?loaded Chitosan Microspheres in vitro, Archives of Pharmacal Research, 27(3) (2004) 346-350.

22. E.M. Kim, H.J. Jeong, In-Kyu Park, C.S. Cho, C.G. Kim, H.S. Bom, Hepatocyte-Targeted Nuclear Imaging Using 99mTc-Galactosylated Chitosan: Conjugation, Targeting, Biodistribution, Journal of Nuclear Medicine, 46(1) (2005) 141-145.

23. T.H.Kim, In-Kyu Park, S.I.Kim, H.J. Jeong, H.S. Bom, Chong Su Cho, Chitosan Derivatives as Gene Carriers, Key Engineering Mataterials, 288-289 (2005) 97-100. 27. In-Kyu Park, S.E. Cook, Y.K. Kim, M.H. Cho, H.J. Jeong, E.M. Kim, J.W. Nah,  H.S. Bom, and C.S. Cho, Glucosylated Polyethylenimine for Tumor-targeting Gene Carrier, Archives of Pharmacal Research, 28(11) (2005) 1302-1310.

33. Y.K.Kim, I.K.Park, H.L.Jiang, R.Arote, H.J.Jeong, E.M.Kim, M.H.Cho, H.S.Bom, C.S.Cho. Glucosylated Polypropylenimine Dendrimer as a Novel Gene Carrier, Key Engineering Materials, 342-343, 457-460(2007).

34. H.Jiang, I.K.Park, M.R.Kang, H.S.Yoo, Y.J.Choi, T.Akaike, C.S.Cho, Immune Stimulating Activity of an Atrophic Rhinitis Vaccine Associated to Pegylated Chitosan Microspheres in Vitro, Polymers for Advanced Tech., 18, 220-225 (2007).

35. In-Kyu Park, Jurate Lasiene, Shinn-Huey Chou, Philip J. Horner, Suzie H. Pun, Efficient, neuron-specific gene delivery mediated by Tet1-modified poly(ethylenimine), Journal of Gene Medicine, 9, 691-702 (2007).

38. In-Kyu Park, Chee-Ping Ng, Jinnan Wang, Baocheng Chu, Chun Yuan, Shanrong Zhang, Suzie H. Pun, Determination of nanoparticle vehicle unpackaging by MR imaging of a T2 magnetic relaxation switch, Biomaterials, 29(6),724-32 (2008).

39. E.J. Kwon, J.M. Bergen, I.K. Park, and S.H. Pun, Peptide-modified vectors for nucleic acid delivery to neurons, Journal of Controlled Release, accepted.

  1. In-Kyu Park et al. Korean Patent, Patent number: 0346577, Date of Patent: July 16, 2002, Galactosylated chitosan-graft-dextran as hepatocyte-targeting DNA carrier.
  2. Chong-Su Cho, In-Kyu Park, Hu-Lin Jiang, Han-Sang Yoo, Sang-Gyun Kang, Patent Issue No.: 10-2004-0080359, Issue date : October 8, 2004, “Pegylated chitosan microspheres for vaccine delivery to enhance immune activity against atrophic rhinitis of swine”.
  3. Mi-Kyung Yoo, In-Kyu Park, Hwan-Jeong Jeong, Yong-Yeon Jeong, Jin-Sook Kwon, Chong-Su Cho, Patent number: 10-0949465, Issue date : March 18, 2010, “Superparamagnetic iron oxide nanoparticles coated with mannan: Preparation method thereof and contrast agent for diagnosing liver diseases”.
  4. Yong Sook Kim, In-Kyu Park, Youngkeun Ahn, Myung Ho Jeong, Won Jong Kim, Sang Yong Jon, Patent Issue No.: 10-2010-0024778, Issue Date: March 19, 2010, “Complex of iron oxide nanoparticles and genes for using in delivery of stem cell genes and method for delivering genes to stem cell by using the same”
  5. Won Jong Kim, Ran Namgung, , In-Kyu Park, Yong Sook Kim, Youngkeun Ahn, , Patent Issue No.: 10-2009-0096314, Issue Date: October 9, 2009, “Development of efficient and safe gene carrier for endothelial cells like HUVEC by polymer/magnetic nanoparticle”
  6. S.J. Yoon, S.Y. Jun, S.H. Kang, Yong Yeon Jeong, In-Kyu Park, Mi-Kyong Yoo, Patent Issue No.: 10-2010-0027634, Issue Date: March 29, 2010, “MRI contrast agent coated with mannose-conjugated polymer and method for producing the same”.
  7. M.H. Cho, C.S. Cho, M.K. Yoo, In-Kyu Park, H.T. Lim, Patent Issue No.: 10-2010-0031028, Issue Date: April 5, 2010, “Folate-PEG-Superparamagnetic Iron Oxide Nanoparticles labeled with Cy5.5 for Lung Cancer Imaging and Contrastmedium for Lung Cancer Imaging containing the same”

 

Achievements

  1. Student Travel Fellowship for Outstanding Student Research in Biomaterials
    - the Sixth World Biomaterials Congress May 15-20, 2000 Hawaii. 
  2. Outstanding Poster Presentation Award
    - the 10th Annual Meeting of Korean Society of Chitin and Chitosan, Feb. 1, 2002, Seoul.
  3. Outstanding Poster Award
    - the 2004 Spring Meeting of the Polymer Society of Korea, April 9, 2004.
  4. Excellence in Research Award & travel grant award
    - the 9th annual meeting of American Society of Gene Therapy, Baltimore, USA, May 31-June 4, 2006.
  5. Award for Best Poster Presentation
    - 2007 International Conference on Nano Science and Nano Technology, Nov. 8, 2007,
    - Kimdaejung Convention Center, Gwangju, Korea
  6. Outstanding Paper Award
    - 2009 Annual Meeting of Korean Society of Chitin and Chitosan, Chung-Ju, Sept. 18, 2009
  7. Best Poster Presentation Award
    - 2009 International Conference on Nano Science and Nano Technology, Mokpo National University, Muan,
    Korea, November 6, 2009.

Book Chapters

  1.  In-Kyu Park, Chong-Su Cho, "Artificial Liver", in Current Trends in Medical Sciences (27): Biomaterials and Tissue Engineering, K.S. Park, T.R. Yoon, M.C. Lee, H.C. Lee, Eds., Chonnam National University Press, Kwang-ju, 2000 (ISBN: 89-7598-227-0).
  2. Chong-Su Cho, In-Kyu Park, "Requirements for conducting Tissue Engineering Research" in Tissue Engineering and Regenerative Medicine, James J. Yoo, Il-Woo Lee, Eds., Koonja Publishing Inc., Seoul, 2002 (ISBN:89-7089-296-6).
  3. Tae Hee Kim, In-Kyu Park, Myung Haing Cho, Jae Woon Nah, Yun Jaie Choi, Toshihiro Akaike, Chong Su Cho, Chitosan Derivatives for Gene Delivery, In New Research in Biomaterials, Denzel R, Bloomington (Eds), Nova Science Publishers, New York, 2007 (ISBN: 1-60021-360-X).
  4. Chong-Su Cho, Yu-Kyoung Oh, Myung-Haing Cho, Choong-Mau Hong, Yeon-Ho Je, Soo Jeong Lim, In-Kyu Park, Won-Jong Kim, Woong Shick Ahn, Youn Joo Park, Kwang Soo Ahn, “Polymer Vector” in Gene Therapy : Focused on Gene Carriers, Seoul National University Press, Seoul, 2009 (ISBN 978-89-521-1052-7)