Assistant Professor, Dept. of Biomedical Science,
Chonnam National University Medical School
Dept. of Biomedical Sciences and Medical Research
Center for Gene Regulation
Chonnam National Univ.
5, Hak-1-dong, Kwanju 501-746
of Korea Tel: +82-62-220-4225 FAX: +82-62-228-4227
Seoul National University B.S. 1996 Natural
Seoul National University M.S. 1998
Natural Fiber Science
Seoul National University Ph.D.
2002 School of Biological Resources and Engineering
2000. 9 ~ 2001. 2 Visiting
Scientist, Tokyo Institute of Technology
~ 2004. 3 Research Associate,
Department of Biomolecular Engineering, Tokyo Institute
4 ~ 2004. 8 Visiting
Researcher, Research Institute for Agriculture and Life
Sciences, Seoul National University
9 ~ 2005. 4 Senior
Scientist, Research Institute for Agriculture and Life
Sciences, Seoul National University
5 ~ 2007. 6 Senior
Fellow, Dept. of Bioengineering, University of Washington.
6 ~ Present Assistant
Professor, Dept. of Biomedical Sciences, Chonnam National
University Medical School.
Main Thrust Areas
Tissue-targeted gene therapy (Heart, cancer, liver,
Design and characterization of tissue-specific
molecular imaging contrast agents (MRI, Optical Imaging)
of Gene-activated matrix for enhanced tissue regeneration
systems of bioactive molecules (Vaccine, proteins)
1. In-Kyu Park, Y.H. Park, B.A. Shin, E.S. Choi,
Y.R. Kim, T. Akaike, C.S. Cho, Galactosylated chitosan-graft-dextran
as hepatocyte-targeting DNA carrier, J. Control. Release,
69 (2000) 97-108
2. In-Kyu Park, Y.H. Park, Preparation and structural
characterization of water-soluble O-hydroxypropyl chitin
derivatives, J. Appl. Polym. Sci., 80 (2001), 2624-2632
7. In-Kyu Park, T.H. Kim, H.Y. Kweon, Y.H. Park,
W.J. Kim, T. Akaike, and C.S. Cho, Visualization of
transfection of galactosylated chitosan-graft-poly(ethylene
glycol) /DNA complexes into hepatocytes by confocal
Laser Scanning Microscopy, Int. J. Pharm., 257 (2003)
9. In-Kyu Park, J. Yang, H.J. Jeong, H.S. Bom, I.
Harada. T. Akaike, S.I. Kim, C.S. Cho, Galactosylated
chitosan as a synthetic extracellular matrix for hepatocytes
attachment, Biomaterials, 24 (2003) 2331-2337.
10. In-Kyu Park, T.H. Kim, S.I. Kim, T. Akaike and
C.S. Cho, Chemical modification of chitosan for the
gene delivery, J. Dispersion Sci. Technol., 24 (2003)
15. S.J. Seo, In-Kyu Park, M.K. Yoo, M.i Shirakawa,
T. Akaike, C.S. Cho, Xyloglucan as a synthetic extracellular
matrix for hepatocytes attachment, Journal of Biomaterials
Science Polymer Ed., 15(11) (2004) 1375-1384.
17. H.L. Jiang, In-Kyu Park, N.R. Shin, H.S. Yoo,
T. Akaike, C.S. Cho, Controlled Release of Vaccine from
Bordetella Bronchiseptica Dermonecrotoxin?loaded Chitosan
Microspheres in vitro, Archives of Pharmacal Research,
27(3) (2004) 346-350.
22. E.M. Kim, H.J. Jeong, In-Kyu Park, C.S. Cho,
C.G. Kim, H.S. Bom, Hepatocyte-Targeted Nuclear Imaging
Using 99mTc-Galactosylated Chitosan: Conjugation, Targeting,
Biodistribution, Journal of Nuclear Medicine, 46(1)
23. T.H.Kim, In-Kyu Park, S.I.Kim, H.J. Jeong, H.S.
Bom, Chong Su Cho, Chitosan Derivatives as Gene Carriers,
Key Engineering Mataterials, 288-289 (2005) 97-100.
27. In-Kyu Park, S.E. Cook, Y.K. Kim, M.H. Cho, H.J.
Jeong, E.M. Kim, J.W. Nah, H.S. Bom, and C.S.
Cho, Glucosylated Polyethylenimine for Tumor-targeting
Gene Carrier, Archives of Pharmacal Research, 28(11)
33. Y.K.Kim, I.K.Park, H.L.Jiang, R.Arote, H.J.Jeong,
E.M.Kim, M.H.Cho, H.S.Bom, C.S.Cho. Glucosylated Polypropylenimine
Dendrimer as a Novel Gene Carrier, Key Engineering Materials,
34. H.Jiang, I.K.Park, M.R.Kang, H.S.Yoo, Y.J.Choi,
T.Akaike, C.S.Cho, Immune Stimulating Activity of an
Atrophic Rhinitis Vaccine Associated to Pegylated Chitosan
Microspheres in Vitro, Polymers for Advanced Tech.,
18, 220-225 (2007).
35. In-Kyu Park, Jurate Lasiene, Shinn-Huey Chou,
Philip J. Horner, Suzie H. Pun, Efficient, neuron-specific
gene delivery mediated by Tet1-modified poly(ethylenimine),
Journal of Gene Medicine, 9, 691-702 (2007).
38. In-Kyu Park, Chee-Ping Ng, Jinnan Wang, Baocheng
Chu, Chun Yuan, Shanrong Zhang, Suzie H. Pun, Determination
of nanoparticle vehicle unpackaging by MR imaging of
a T2 magnetic relaxation switch, Biomaterials, 29(6),724-32
39. E.J. Kwon, J.M. Bergen, I.K. Park, and S.H. Pun,
Peptide-modified vectors for nucleic acid delivery to
neurons, Journal of Controlled Release, accepted.
- In-Kyu Park et al. Korean Patent, Patent number:
0346577, Date of Patent: July 16, 2002, Galactosylated
chitosan-graft-dextran as hepatocyte-targeting DNA
- Chong-Su Cho, In-Kyu Park, Hu-Lin Jiang, Han-Sang
Yoo, Sang-Gyun Kang, Patent Issue No.: 10-2004-0080359,
Issue date : October 8, 2004, “Pegylated chitosan
microspheres for vaccine delivery to enhance immune
activity against atrophic rhinitis of swine”.
- Mi-Kyung Yoo, In-Kyu Park, Hwan-Jeong Jeong,
Yong-Yeon Jeong, Jin-Sook Kwon, Chong-Su Cho, Patent
number: 10-0949465, Issue date : March 18, 2010,
“Superparamagnetic iron oxide nanoparticles coated
with mannan: Preparation method thereof and contrast
agent for diagnosing liver diseases”.
- Yong Sook Kim, In-Kyu Park, Youngkeun Ahn, Myung
Ho Jeong, Won Jong Kim, Sang Yong Jon, Patent Issue
No.: 10-2010-0024778, Issue Date: March 19, 2010,
“Complex of iron oxide nanoparticles and genes
for using in delivery of stem cell genes and method
for delivering genes to stem cell by using the same”
- Won Jong Kim, Ran Namgung, , In-Kyu Park, Yong
Sook Kim, Youngkeun Ahn, , Patent Issue No.: 10-2009-0096314,
Issue Date: October 9, 2009, “Development of efficient
and safe gene carrier for endothelial cells like
HUVEC by polymer/magnetic nanoparticle”
- S.J. Yoon, S.Y. Jun, S.H. Kang, Yong Yeon Jeong,
In-Kyu Park, Mi-Kyong Yoo, Patent Issue No.: 10-2010-0027634,
Issue Date: March 29, 2010, “MRI contrast agent
coated with mannose-conjugated polymer and method
for producing the same”.
- M.H. Cho, C.S. Cho, M.K. Yoo, In-Kyu Park, H.T.
Lim, Patent Issue No.: 10-2010-0031028, Issue Date:
April 5, 2010, “Folate-PEG-Superparamagnetic Iron
Oxide Nanoparticles labeled with Cy5.5 for Lung
Cancer Imaging and Contrastmedium for Lung Cancer
Imaging containing the same”
- Student Travel Fellowship for Outstanding Student
Research in Biomaterials
- the Sixth World Biomaterials
Congress May 15-20, 2000 Hawaii.
- Outstanding Poster Presentation Award
10th Annual Meeting of Korean Society of Chitin
and Chitosan, Feb. 1, 2002, Seoul.
- Outstanding Poster Award
- the 2004 Spring
Meeting of the Polymer Society of Korea, April 9,
- Excellence in Research Award & travel grant
- the 9th annual meeting of American Society
of Gene Therapy, Baltimore, USA, May 31-June 4,
- Award for Best Poster Presentation
International Conference on Nano Science and Nano
Technology, Nov. 8, 2007,
- Kimdaejung Convention
Center, Gwangju, Korea
- Outstanding Paper Award
- 2009 Annual Meeting
of Korean Society of Chitin and Chitosan, Chung-Ju,
Sept. 18, 2009
- Best Poster Presentation Award
- 2009 International
Conference on Nano Science and Nano Technology,
Mokpo National University, Muan,
- In-Kyu Park, Chong-Su Cho, "Artificial
Liver", in Current Trends in Medical Sciences
(27): Biomaterials and Tissue Engineering, K.S.
Park, T.R. Yoon, M.C. Lee, H.C. Lee, Eds., Chonnam
National University Press, Kwang-ju, 2000 (ISBN:
- Chong-Su Cho, In-Kyu Park, "Requirements
for conducting Tissue Engineering Research"
in Tissue Engineering and Regenerative Medicine,
James J. Yoo, Il-Woo Lee, Eds., Koonja Publishing
Inc., Seoul, 2002 (ISBN:89-7089-296-6).
- Tae Hee Kim, In-Kyu Park, Myung Haing Cho, Jae
Woon Nah, Yun Jaie Choi, Toshihiro Akaike, Chong
Su Cho, Chitosan Derivatives for Gene Delivery,
In New Research in Biomaterials, Denzel R, Bloomington
(Eds), Nova Science Publishers, New York, 2007 (ISBN:
- Chong-Su Cho, Yu-Kyoung Oh, Myung-Haing Cho,
Choong-Mau Hong, Yeon-Ho Je, Soo Jeong Lim, In-Kyu
Park, Won-Jong Kim, Woong Shick Ahn, Youn Joo Park,
Kwang Soo Ahn, “Polymer Vector” in Gene Therapy
: Focused on Gene Carriers, Seoul National University
Press, Seoul, 2009 (ISBN 978-89-521-1052-7)